By June 2025, NAD+ IV treatment had surged in popularity among Hollywood stars seeking longevity, mental clarity, and boosted energy.
Celebrities like Hailey Bieber, Kendall Jenner, Jennifer Aniston, and Gwyneth Paltrow have all publicly backed the therapy.
On 12 March 2025, Forbes Business Council linked NAD+ interest to biohacking trends and rising demand for preventive wellness among the wealthy in its coverage of “The Next Frontier of Biohacking”.
WHAT IS NAD+IV AND WHY IS IT BECOMING POPULAR?
The body naturally makes NAD+ (nicotinamide adenine dinucleotide), a molecule that supports cell repair, energy production, and overall function. As one ages, their levels decrease.
Moreover, some clinics (Drip Hydration, New Hope Wellness) provide intravenous drips of NAD+, which they claim can slow down ageing and restore vitality.
Dr David Sinclair of Harvard suggests combining it with nicotinamide mononucleotide (NMN) to increase longevity.
However, the Food and Drug Administration (FDA) has not approved NAD+ intravenous (IV) therapy, and its long-term effects remain under study.
CELEBRITY BACKING THE BUZZ
By the middle of 2025, celebrity endorsements of NAD+ IV therapy had made it very popular around the world.
Hailey Bieber and Kendall Jenner, for example, showed off their treatments on The Kardashians (2022).
The culture of influencers and biohacking podcasts has made people even more interested in the therapy’s supposed anti-ageing effects.
Fees vary from clinic to clinic, but sessions can cost up to $1 000 (R18 018) per infusion, depending on the provider, the dose, and the time of administration.
DOCTORS WARN AGAINST HYPE OF NAD+
Not all health professionals are completely in support of NAD+ IV treatment.
Dr. Pieter Cohen from Harvard Medical School says that “comprehensive long-term human studies are absent.”
Dr. Cohen also emphasises the need for personalised medical care, especially with high-dose IV therapies.
The NIH has paid for research on NAD+ precursors like NR and NMN in the past, but it has not approved NAD+ IV treatment.
Medical groups continue to call for more regulation and openness in the clinical setting.
GIVEN ITS POSSIBLE ANTI-AGEING PROPERTIES, WOULD YOU CONSIDER NAD+ THERAPY?
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